Miliary Tuberculosis in an Immunocompetent Patient Presenting with Tuberculous Meningoencephalitis Complicated by Hydrocephalus and Seizures

Miliary tuberculosis (MTB) is a disseminated form of tuberculosis (TB) arising from the lymphohematogenous dissemination of <i>Mycobacterium tuberculosis</i> bacilli followed by millet seed-sized tuberculous foci. It mainly affects immunocompromised patients and can lead to severe complications or even death. The clinical manifestation is diverse and depends on the organ affected, the patient's immune status, and the possible involvement of the central nervous system (CNS). Hence, this case report presents a case of an immunocompetent male with a decreased level of consciousness and convulsions requiring admission to the intensive care unit. The patient was diagnosed with MTB, meningoencephalitis, hydrocephalus, and severe hyponatremia. He subsequently improved after a short period of initiation of anti-TB medications. This report also highlights the clinical features of MTB and reviews the literature on associated CNS complications of MTB.

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Journal
Journal of Global Infectious Diseases
Published
2025-04-01
DOI
https://doi.org/10.4103/jgid.jgid_111_24
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
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article

Miliary Tuberculosis in an Immunocompetent Patient Presenting with Tuberculous Meningoencephalitis Complicated by Hydrocephalus and Seizures

Shaya Y. AlQahtani, Ahmed Alsahlawi, Marwan Jabr Alwazzeh, Sara Alwarthan et al.
Journal of Global Infectious Diseases
Infectious Diseases and Tuberculosis
article

Miliary Tuberculosis in an Immunocompetent Patient Presenting with Tuberculous Meningoencephalitis Complicated by Hydrocephalus and Seizures

Shaya Y. AlQahtani, Ahmed Alsahlawi, Marwan Jabr Alwazzeh, Sara Alwarthan, Mudar Alwazzeh, Mohanad A. Alkuwaiti, Mohammed Dhafer, Albaraa Juraybi
article en

Abstract

Miliary tuberculosis (MTB) is a disseminated form of tuberculosis (TB) arising from the lymphohematogenous dissemination of <i>Mycobacterium tuberculosis</i> bacilli followed by millet seed-sized tuberculous foci. It mainly affects immunocompromised patients and can lead to severe complications or even death. The clinical manifestation is diverse and depends on the organ affected, the patient's immune status, and the possible involvement of the central nervous system (CNS). Hence, this case report presents a case of an immunocompetent male with a decreased level of consciousness and convulsions requiring admission to the intensive care unit. The patient was diagnosed with MTB, meningoencephalitis, hydrocephalus, and severe hyponatremia. He subsequently improved after a short period of initiation of anti-TB medications. This report also highlights the clinical features of MTB and reviews the literature on associated CNS complications of MTB.

Journal of Global Infectious DiseasesVol. 17(2)
King Fahd Hospital of the University (SA), Al Andalus University (SY), Imam Abdulrahman Bin Faisal University (SA)
Good health and well-being
Openalex Percentile: Top 81%
Infectious Diseases and Tuberculosis
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