Platelet transfusion induces transfusion‐associated circulatory overload in rats with myocardial infarction
Platelet transfusion induces circulatory overload in a TACO rat model with heart failure when compared to crystalloids, showing a trend toward reduced oxygenation compared to plasma transfusion. Further investigation is needed to determine the pathophysiological mechanisms.
Authors
- Charissa E. van den Brom (ORCID: https://orcid.org/0000-0002-0886-1388)
- Rick Kapur (ORCID: https://orcid.org/0000-0002-1608-876X)
- Anita M. Tuip‐de Boer (ORCID: https://orcid.org/0000-0002-7594-2364)
- Robert B. Klanderman
- Philippa G. Phelp (ORCID: https://orcid.org/0009-0002-0093-3241)
- Alexander P. J. Vlaar (ORCID: https://orcid.org/0000-0002-3453-7186)
- Joris J. T. H. Roelofs (ORCID: https://orcid.org/0000-0001-9595-6571)
- Chantal A. Polet
- Britt Hurks
Institutions
- Sanquin (NL)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Transfusion
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1111/trf.18285
- Citations
- 1
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Landsteiner Foundation for Blood Transfusion Research
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek