Shared neoantigens’ atlas for off-the-shelf cancer vaccine development
This represents the first in-depth analysis for the identification of a specific repertoire of shared mutated NeoAgs, most of which never reported before. Such shared SNV and InDel-NeoAgs are indispensable for the development of "off-the-shelf" cancer vaccines targeting a relevant percentage of cancers in a significant percentage of cancer patients worldwide.
Authors
- Luigi Buonaguro (ORCID: https://orcid.org/0000-0002-6380-7114)
- Angela Mauriello (ORCID: https://orcid.org/0000-0002-0133-7540)
- Maria Tagliamonte (ORCID: https://orcid.org/0000-0002-7167-4817)
- Concetta Ragone (ORCID: https://orcid.org/0000-0002-9521-6802)
- Beatrice Cavalluzzo (ORCID: https://orcid.org/0000-0002-3254-0322)
Institutions
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12967-025-06478-3
- Citations
- 3
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 2.39
Funders
- Ministero della Salute