Increased Recall of Negative Memories Following Initial Methylphenidate Administration in a 6‐Year‐Old Boy With <scp>ADHD</scp>: A Case Report
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that begins in childhood and can persist into adolescence and adulthood. Stimulants, particularly methylphenidate and amphetamines, are the first-line treatments for ADHD in children and adolescents. While the potential for stimulants to induce psychosis-like or mania-like symptoms in children has been recognized for decades, there have been no reported cases of increased recall of negative memories associated with methylphenidate. Here, we present a rare case in which an initial dose of 18 mg of Methylphenidate Hydrochloride Extended-Release Tablets led to increased recall of negative life events in a 6-year-old child with ADHD. Interestingly, the symptom resolved spontaneously the following day without discontinuing the medication, suggesting that it was an adaptive response rather than a toxic reaction.
Authors
- Youguo Tan (ORCID: https://orcid.org/0000-0002-4892-3758)
- Qingqing Xiang
- A. Ye
- Yiguo Feng
- Bo Liu (ORCID: https://orcid.org/0009-0009-1797-1069)
- Liling Xu (ORCID: https://orcid.org/0000-0002-5128-2947)
Institutions
- Southwest Medical University (CN)
- Zigong First People's Hospital (CN)
Publication Details
- Journal
- Neuropsychopharmacology Reports
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/npr2.70026
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 0.00