Nonpharmacologic Management of Recurrent Painful Ophthalmoplegic Neuropathy: A Case Report

Recurrent painful ophthalmoplegic neuropathy (RPON) is a rare neurologic disorder characterized by headaches and ocular cranial nerve paresis with no consensus on optimal treatment. While pharmacologic treatments are commonly used, limited research has explored nonpharmacologic options. A 36-year-old woman with a multi-year history of episodes of RPON lasting several months presented to a chiropractor with a week-long episode of headache and diplopia unresponsive to oral steroids and sumatriptan. Spinal manipulation and acupuncture were administered over six weeks, leading to complete symptom resolution. This is a case of RPON managed successfully with chiropractic care and acupuncture, suggesting a potential beneficial role of these therapies. Given the limitations of a single case, further research is warranted to determine the effectiveness of these therapies for RPON.

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Publication Details

Journal
Cureus
Published
2025-05-19
DOI
https://doi.org/10.7759/cureus.84387
Primary Topic
Pain Mechanisms and Treatments
Type
article
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article

Nonpharmacologic Management of Recurrent Painful Ophthalmoplegic Neuropathy: A Case Report

Robert J. Trager, Tyler D. Kemp
Cureus
Pain Mechanisms and Treatments
article

Nonpharmacologic Management of Recurrent Painful Ophthalmoplegic Neuropathy: A Case Report

Robert J. Trager, Tyler D. Kemp
article en

Abstract

Recurrent painful ophthalmoplegic neuropathy (RPON) is a rare neurologic disorder characterized by headaches and ocular cranial nerve paresis with no consensus on optimal treatment. While pharmacologic treatments are commonly used, limited research has explored nonpharmacologic options. A 36-year-old woman with a multi-year history of episodes of RPON lasting several months presented to a chiropractor with a week-long episode of headache and diplopia unresponsive to oral steroids and sumatriptan. Spinal manipulation and acupuncture were administered over six weeks, leading to complete symptom resolution. This is a case of RPON managed successfully with chiropractic care and acupuncture, suggesting a potential beneficial role of these therapies. Given the limitations of a single case, further research is warranted to determine the effectiveness of these therapies for RPON.

CureusVol. 17(5)
University Hospitals of Cleveland (US), Cleveland University (US), Canadian Chiropractic Association (CA)
Openalex Percentile: Top 85%
Pain Mechanisms and Treatments
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