2-Pyridone-enabled manganese-catalyzed <i>ortho</i>-selective deuteration of aromatic amides with D<sub>2</sub>O
A manganese-catalyzed protocol for the ortho -selective deuteration of aromatic amides has been developed, featuring Mn(CO) 5 Br as the catalyst, 2-pyridone-assisted C–H activation, and D 2 O as the deuterium source.
Authors
- Jian‐Fei Bai (ORCID: https://orcid.org/0000-0002-9128-5819)
- Zhanghua Gao (ORCID: https://orcid.org/0000-0002-6950-8609)
- Zhi‐Jiang Jiang (ORCID: https://orcid.org/0000-0003-2323-1840)
- Jia Chen (ORCID: https://orcid.org/0000-0003-1541-2617)
- Qian Tao (ORCID: https://orcid.org/0000-0002-8170-969X)
- Jinfeng Zheng
Institutions
- University of Nottingham Ningbo China (CN)
- Ningbo University of Technology (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00606f
- Citations
- 1
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 0.79
Funders
- Startup Foundation
- National Natural Science Foundation of China
- Ningbo Municipal Bureau of Science and Technology