Aculeunas: Exploring the Antimicrobial Properties of Mayana (Coleus Blumei) and Cavendish Banana (Musa Acuminata) Pseudostem Pure Extract Against Pseudomonas Aeruginosa

Bacterial infections from Pseudomonas aeruginosa have been causing problems due to its resistance to antibiotics and ability to adapt in diverse environments and healthcare settings. To address this growing concern, this research was conducted to investigate the antimicrobial properties of mayana leaf extract with cavendish banana pseudostem pure extract as a potential alternative treatment in inhibiting the growth of P. aeruginosa. The extracts were obtained using ethanol maceration for Mayana leaves and simple distillation, while hand pressing as an alternative for extracting the pure extract of the banana pseudostem. Three different concentrations of the combined extracts were tested using the Kirby-Bauer test, with povidone-iodine as a positive control. The results showed that the combined extracts exhibited significant antimicrobial activity with inhibition zones comparable to the commercial treatment. However, the test result showed that there is no significant difference (p ≥ 0.05, p = 0.55) compared to the treatment. These findings suggest that Mayana leaf and Cavendish banana pseudostem extracts have potential as natural antibacterial agents against P. aeruginosa, and further studies should be conducted to explore its efficacy against bacteria.