NeuroD1 is frequently expressed in Merkel cell polyomavirus-negative and keratin 20-negative Merkel cell carcinoma: A potential diagnostic pitfall
NeuroD1-positive MCCs are significantly correlated with MCPyV-negative, keratin 20-negative expression, and focal TTF1 expression. NeuroD1 expression can pose a potential diagnostic pitfall in the distinction of MCC from SCLC, especially in a setting of a limited immunohistochemical panel.
Authors
- Mai P. Hoang (ORCID: https://orcid.org/0000-0002-1406-7981)
- Paweł Karpiński (ORCID: https://orcid.org/0000-0003-3885-694X)
- Cheng-Lin Wu (ORCID: https://orcid.org/0000-0002-1331-2092)
Institutions
- Harvard University (US)
- Wroclaw Medical University (PL)
- Massachusetts General Hospital (US)
- National Cheng Kung University Hospital (TW)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2025-04-15
- DOI
- https://doi.org/10.1093/ajcp/aqaf046
- Citations
- 1
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.05