Potential biological targets prediction and adme profiling of methyl group containing phenyl hydrazones

Hydrazones characterized by the azomethine group (NHN=CH-) are recognized for their potent antimicrobial properties. Concurrently, compounds featuring a methyl group are utilized in the treatment of bacterial infections in humans and animals. Taking all this into account, Swiss ADME and Swiss Targeted Prediction software was used to study biological targets of the synthesized compounds and to create their ADME profiles. New biological targets for phenylhydrazones include Mapping of Bioavailability Radar of substances, ADME Profiling, Egan BOILED EGG, Lipinski Drug ability (ROF) criteria and biological activities based on the obtained results. Thus, obtained results allow us to say that synthesized phenylhydrazones are able to show biological activity.