Proteomic characteristics of bronchoalveolar lavage fluid in children with mild and severe Mycoplasma pneumoniae pneumonia
Differences in the proteomic characteristics of bronchoalveolar lavage fluid in children with mild and severe <i>Mycoplasma pneumoniae</i> pneumonia (MPP) were identified, revealing the role of lung-specific immunologic and inflammatory response in the pathogenesis of MPP. Given the increasing incidence of severe MPP in children in recent years and the emergence of macrolide-resistant <i>M. pneumoniae</i> infection in some regions, our findings provided valuable knowledge and insights into the pathogenesis of <i>M. pneumoniae</i> infection.
Authors
- Qingyan Zhang
- Chunchen Wu (ORCID: https://orcid.org/0000-0002-6888-213X)
- Jianbo Xia (ORCID: https://orcid.org/0000-0002-8912-9921)
- Ao Liang (ORCID: https://orcid.org/0009-0006-9826-454X)
- Anbang Wang (ORCID: https://orcid.org/0000-0002-0548-3182)
- Yafang He
- Xiaoxue Wu
- Yaqi Zhu (ORCID: https://orcid.org/0009-0009-1857-2676)
Institutions
- Hubei University of Chinese Medicine (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Wuhan Prevention and Treatment Center for Occupational Diseases (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fmicb.2025.1595521
- Citations
- 2
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71