DNA Methylation of <i>iNOS</i>, <i>eNOS, TP53</i> and LINE‐1 in Gingival Tissues of Cigarette Smokers, Heat‐Not‐Burn Smokers and Never Smokers: An Exploratory Study
HnB device smoking increased DNA methylation levels of iNOS gene, which might indicate a decreased iNOS expression in HnB smokers, compared to traditional smokers and never smokers. Implications of the observed iNOS methylation status in the development of oral cancer needs to be investigated in future studies.
Authors
- Valentina Bollati (ORCID: https://orcid.org/0000-0002-0370-9598)
- Alessia Moiana
- G Bellucci (ORCID: https://orcid.org/0000-0002-1240-8340)
- Dario Consonni (ORCID: https://orcid.org/0000-0002-8935-3843)
- Farah Asa’ad (ORCID: https://orcid.org/0000-0001-5186-2645)
- Giulio Rasperini (ORCID: https://orcid.org/0000-0003-3836-147X)
- Michele Codari
- Letizia Tarantini (ORCID: https://orcid.org/0009-0003-9191-4237)
- Lena Larsson (ORCID: https://orcid.org/0000-0002-6619-6136)
Institutions
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- University of Gothenburg (SE)
Publication Details
- Journal
- Clinical and Experimental Dental Research
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/cre2.70141
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81