Cutaneous dysbiosis in girls with vulvar lichen sclerosus

Cutaneous dysbiosis in vulvar lichen sclerosus (VLS) may play a key role in disease pathogenesis, especially when specific microbial imbalances persist in affected patients. However, most clinical evaluations focus on symptoms rather than microbial composition, risking missed opportunities for microbiome-targeted interventions. Thus, this study highlights the importance of microbiota surveillance as a potential tool for improving the diagnosis and treatment of VLS.

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Publication Details

Journal
Microbiology Spectrum
Published
2025-05-19
DOI
https://doi.org/10.1128/spectrum.02674-24
Citations
2
Primary Topic
Genital Health and Disease
Type
article
Field-Weighted Citation Impact
4.01
Controls
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article

Cutaneous dysbiosis in girls with vulvar lichen sclerosus

Fengxia Li, Chaoqun Wang, Li‐Ying Sun, Lan Yu et al.
2 citations
Microbiology Spectrum
Genital Health and Disease
4.01
article

Cutaneous dysbiosis in girls with vulvar lichen sclerosus

Fengxia Li, Chaoqun Wang, Li‐Ying Sun, Lan Yu, Qiuxiang Shen, Lingling Jin, Dandan Chen, Cheng Ren, Li Zhu, Junwen Zhang, H. Gao, Hongyu Chen
article en
2 citations

Abstract

Cutaneous dysbiosis in vulvar lichen sclerosus (VLS) may play a key role in disease pathogenesis, especially when specific microbial imbalances persist in affected patients. However, most clinical evaluations focus on symptoms rather than microbial composition, risking missed opportunities for microbiome-targeted interventions. Thus, this study highlights the importance of microbiota surveillance as a potential tool for improving the diagnosis and treatment of VLS.

Microbiology SpectrumVol. 13(7)
Children's Hospital of Zhejiang University (CN), National Clinical Research (US)
Life in Land
Openalex Percentile: Top 7%
Genital Health and Disease
4.01
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Cutaneous dysbiosis in girls with vulvar lichen sclerosus — Fengxia Li, Chaoqun Wang, et al. · Microbiology Spectrum (2025) | TGRS Research Map | TGRS