Performance of the bioLytical Multiplex HIV 1/2 and Syphilis rapid test on serum in a laboratory evaluation for syphilis
We examined the performance of the syphilis antibody component of a rapid multiplex device and found that sera with RPR titers of 1:8 and greater, often found in infectious syphilis, were highly likely to test positive. This device would be suitable for providing STAT syphilis serology testing for suspect cases waiting in the Emergency Department or as inpatients. Positive results can support immediate treatment and linkage to care, especially for pregnant females and transient persons who are often lost to follow up.
Authors
- Graham Tipples (ORCID: https://orcid.org/0000-0002-2116-8553)
- Hong Zhou (ORCID: https://orcid.org/0000-0002-5104-3196)
- Ameeta E. Singh (ORCID: https://orcid.org/0000-0003-2627-3704)
- Jennifer Gratrix (ORCID: https://orcid.org/0000-0001-6999-9201)
- Rick Galli
- Bárbara Rivera (ORCID: https://orcid.org/0000-0001-9434-6288)
- Sean B. Rourke (ORCID: https://orcid.org/0000-0001-7079-5126)
- Kevin Fonseca (ORCID: https://orcid.org/0000-0003-0294-0963)
- Emily McCullough
- Anastasia Eliopoulos
Institutions
- Alberta Health Services (CA)
- St. Michael's Hospital (CA)
- University of Alberta (CA)
- University of Calgary (CA)
- University of Toronto (CA)
- Health Solutions (Sweden) (SE)
- St Michaels Hospital (GB)
- Unity Health Toronto
- Public Health Laboratory
Publication Details
- Journal
- Microbiology Spectrum
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1128/spectrum.00132-25
- Citations
- 2
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.33