The natural history of anal high-grade squamous intraepithelial lesions among MSM and transgender women in an acute HIV cohort in Thailand
Among predominantly young participants initiating antiretroviral therapy during acute HIV acquisition, anal HSIL showed high incidence yet markedly high clearance rates. Anal HPV 16 infection increased risk of incident anal HSIL and decreased lesion clearance. HPV vaccination and HSIL screening/treatment should be implemented despite rapid antiretroviral therapy initiation.
Authors
- Piranun Hongchookiat
- Tippawan Pankam (ORCID: https://orcid.org/0000-0002-0546-1370)
- Kultida Poltavee
- Sumitr Tongmuang
- Supanat Thitipatarakorn (ORCID: https://orcid.org/0000-0003-3639-549X)
- Pravit Mingkwanrungruang
- Reshmie Ramautarsing (ORCID: https://orcid.org/0000-0002-6293-9422)
- Nittaya Phanuphak (ORCID: https://orcid.org/0000-0002-0036-3165)
- Carlo Sacdalan (ORCID: https://orcid.org/0000-0002-5839-4837)
- Nitiya Chomchey (ORCID: https://orcid.org/0000-0002-0539-4542)
- Siriporn Nonenoy
- Sujittra Suriwong
- Nipat Teeratakulpisarn
- Stephen John Kerr (ORCID: https://orcid.org/0000-0002-1919-4525)
- Donn Colby (ORCID: https://orcid.org/0000-0003-3931-5926)
- Aphakan Klinsukontakul
- Napasawan Chinlaertworasiri
Institutions
- Thai Red Cross Society (TH)
- Chulalongkorn University (TH)
- UNSW Sydney (AU)
- Rattana Bundit University (TH)
- HIV Netherlands Australia Thailand Research Collaboration (TH)
- Institut de Recherche et d’Innovation (FR)
Publication Details
- Journal
- AIDS
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1097/qad.0000000000004238
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00