Exosomes derived from M2 macrophages regulate airway inflammation by modulating epithelial cell proliferation and apoptosis
These findings demonstrate that M2Φ-Exos regulate the imbalance in epithelial proliferation and apoptosis in asthma, reducing inflammation and mitigating tissue remodeling, and provide new insights into potential therapeutic strategies for asthma management.
Authors
- Fengxia Ding
- Yuehan Li (ORCID: https://orcid.org/0000-0003-3244-0353)
- Yinying Ren
- Fang Deng (ORCID: https://orcid.org/0000-0002-7927-5394)
- Zhou Fu (ORCID: https://orcid.org/0000-0001-9024-3222)
- Enmei Liu (ORCID: https://orcid.org/0000-0001-8503-6974)
- Bo Liu (ORCID: https://orcid.org/0000-0001-9918-7749)
- Yan Li (ORCID: https://orcid.org/0009-0009-5126-6558)
- Jinyue Yu
- Zhengxiu Luo (ORCID: https://orcid.org/0000-0003-2569-753X)
- Mi Zhou
- JinYing Xiang
Institutions
- Great Ormond Street Hospital (GB)
- University of Bristol (GB)
- University College London (GB)
Publication Details
- Journal
- Journal of Inflammation
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12950-025-00444-y
- Citations
- 6
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- China Postdoctoral Science Foundation