Concentrated growth factor with guided tissue regeneration for shallow infrabony defects: A one‐year prospective study
This study explored a novel approach to treating shallow bone defects around teeth using a combination of concentrated growth factor (CGF) sticky bone and guided tissue regeneration (GTR). The treatment involved using a specially prepared bone graft material (CGF sticky bone) along with a collagen membrane and a CGF membrane. The researchers tracked the changes in gum and bone health in 13 patients with 31 shallow defects over 1 year. The results showed significant improvements: Gum attachment levels increased by an average of 2.48 mm, gum pockets reduced by 2.90 mm, and bone growth averaged 2.46 mm. Notably, gum recession and gingival contour remained stable, meaning the treatment did not compromise the appearance of the gums. The study also found that patients with worse gum or bone loss at the start of the treatment tended to experience the greatest improvements. These findings suggest that CGF sticky bone combined with GTR is a promising option for restoring shallow bone defects, particularly in cases where traditional therapy has left residual gum pockets.
Authors
- Xiangying Ouyang (ORCID: https://orcid.org/0000-0003-3703-0847)
- Jianru Liu
- Siniong Iao (ORCID: https://orcid.org/0000-0001-5004-4667)
- Wenyi Liu (ORCID: https://orcid.org/0000-0003-2069-0865)
- Yan Huang (ORCID: https://orcid.org/0009-0003-9166-1225)
Institutions
- Peking University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- Journal of Periodontology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/jper.24-0728
- Citations
- 1
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.84