Concentrated growth factor with guided tissue regeneration for shallow infrabony defects: A one‐year prospective study

This study explored a novel approach to treating shallow bone defects around teeth using a combination of concentrated growth factor (CGF) sticky bone and guided tissue regeneration (GTR). The treatment involved using a specially prepared bone graft material (CGF sticky bone) along with a collagen membrane and a CGF membrane. The researchers tracked the changes in gum and bone health in 13 patients with 31 shallow defects over 1 year. The results showed significant improvements: Gum attachment levels increased by an average of 2.48 mm, gum pockets reduced by 2.90 mm, and bone growth averaged 2.46 mm. Notably, gum recession and gingival contour remained stable, meaning the treatment did not compromise the appearance of the gums. The study also found that patients with worse gum or bone loss at the start of the treatment tended to experience the greatest improvements. These findings suggest that CGF sticky bone combined with GTR is a promising option for restoring shallow bone defects, particularly in cases where traditional therapy has left residual gum pockets.

Authors

Institutions

Publication Details

Journal
Journal of Periodontology
Published
2025-05-19
DOI
https://doi.org/10.1002/jper.24-0728
Citations
1
Primary Topic
Periodontal Regeneration and Treatments
Type
article
Field-Weighted Citation Impact
1.84
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Concentrated growth factor with guided tissue regeneration for shallow infrabony defects: A one‐year prospective study

Xiangying Ouyang, Jianru Liu, Siniong Iao, Wenyi Liu et al.
1 citations
Journal of Periodontology
Periodontal Regeneration and Treatments
1.84
article

Concentrated growth factor with guided tissue regeneration for shallow infrabony defects: A one‐year prospective study

Xiangying Ouyang, Jianru Liu, Siniong Iao, Wenyi Liu, Yan Huang
article en
1 citations

Abstract

This study explored a novel approach to treating shallow bone defects around teeth using a combination of concentrated growth factor (CGF) sticky bone and guided tissue regeneration (GTR). The treatment involved using a specially prepared bone graft material (CGF sticky bone) along with a collagen membrane and a CGF membrane. The researchers tracked the changes in gum and bone health in 13 patients with 31 shallow defects over 1 year. The results showed significant improvements: Gum attachment levels increased by an average of 2.48 mm, gum pockets reduced by 2.90 mm, and bone growth averaged 2.46 mm. Notably, gum recession and gingival contour remained stable, meaning the treatment did not compromise the appearance of the gums. The study also found that patients with worse gum or bone loss at the start of the treatment tended to experience the greatest improvements. These findings suggest that CGF sticky bone combined with GTR is a promising option for restoring shallow bone defects, particularly in cases where traditional therapy has left residual gum pockets.

Journal of PeriodontologyVol. 97(1)
Peking University (CN), National Clinical Research Center for Digestive Diseases (CN)
Openalex Percentile: Top 17%
Periodontal Regeneration and Treatments
1.84
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.