Butyrylcholinesterase and 24 h-urinary copper excretion as compliance assessment in long-term treated Wilson’s disease
When compliance of WD-patients is classified on the basis of their 24 h-urinary copper excretion CHE-S is more sensitive to detect problems of non-compliance than serum levels of copper, of non-ceruloplasmin bound free copper or ceruloplasmin. Therefore, CHE-S may be used as an easy to determine further biomarker for compliance assessment in long-term treatment of WD in addition to 24 h-UCU.
Authors
- Tom Luedde (ORCID: https://orcid.org/0000-0002-6288-8821)
- Sara Samadzadeh (ORCID: https://orcid.org/0000-0003-3593-1852)
- Philipp Albrecht (ORCID: https://orcid.org/0000-0001-7987-658X)
- Sven Guenther Meuth (ORCID: https://orcid.org/0000-0003-2571-3501)
- Harald Hefter (ORCID: https://orcid.org/0000-0003-1069-7684)
- Max Novak
- Dietmar Rosenthal
- Christian J. Hartmann (ORCID: https://orcid.org/0000-0002-8296-8626)
Institutions
- University of Southern Denmark (DK)
- Kliniken Maria Hilf (DE)
- Slagelse Hospital (DK)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.3389/fneur.2025.1553573
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00