Anti-PD-1 synergizes with RFA to suppress abscopal tumors and induce durable memory against recurrence in HCC
Our study discovered that RFA combined with anti-PD-1 induced anti-tumor immunity to inhibit abscopal tumors and durable immune memory to prevent recurrence, suggesting RFA+anti-PD-1 as a potential therapeutic strategy for multifocal HCC and preventing recurrence.
Authors
- Kai Lei (ORCID: https://orcid.org/0000-0002-1548-6862)
- Xuezhen Zeng (ORCID: https://orcid.org/0000-0002-0241-6144)
- Shuang Li (ORCID: https://orcid.org/0000-0002-6828-5925)
- Jiale Chen (ORCID: https://orcid.org/0009-0005-3959-6416)
- Fang Wang (ORCID: https://orcid.org/0000-0002-8111-8603)
- Zebin Chen
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Liver Research
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1016/j.livres.2025.05.003
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00