Multiple bluish papules and nodules in a 12-year-old child with lower gastrointestinal bleeding: a diagnostic challenge
Blue rubber bleb nevus syndrome (BRBNS) and familial multiple glomuvenous malformations (GVM) are genetic disorders characterized by multiple cutaneous vascular malformations. Unlike multiple GVM, BRBNS comprises a risk of systemic involvement with vascular malformations in other organs, potentially causing life-threatening bleeding. The correct distinction between these two conditions is challenging due to their clinical similarity, but it is crucial in light of the pivotal differences in prognosis and follow-up. We report a case of multiple glomuvenous malformations in a child with lower gastrointestinal bleeding that posed a thought-provoking diagnosis.
Authors
- Lanyu Sun (ORCID: https://orcid.org/0000-0003-2148-1715)
- Sónia Fernandes (ORCID: https://orcid.org/0000-0002-6936-2048)
- Claudia Brazao
- Luís Soares‐de‐Almeida (ORCID: https://orcid.org/0000-0003-4026-6105)
- L. Miguel Rodrigues (ORCID: https://orcid.org/0000-0002-6949-565X)
- Michelle Rodrigues (ORCID: https://orcid.org/0000-0002-9747-1882)
- Sofia Antunes‐Duarte (ORCID: https://orcid.org/0000-0003-3662-0423)
- Dora Mancha (ORCID: https://orcid.org/0000-0002-6536-8936)
- Pedro de Vasconcelos (ORCID: https://orcid.org/0000-0002-7480-1228)
- Paulo Filipe (ORCID: https://orcid.org/0000-0001-6917-527X)
Institutions
- Hospital de Santa Maria (PT)
Publication Details
- Journal
- Dermatology Online Journal
- Published
- 2025-05-19
- DOI
- https://doi.org/10.5070/d331265296
- Primary Topic
- Eosinophilic Disorders and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 0.00