Prediction of Grade 4 radiation-induced lymphopenia during chemoradiation therapy for lung cancer patients: Insights from two past trials
Baseline ALC and lung V<sub>5Gy</sub> were identified as predictors for G4-RIL, consistent with findings from previous studies. Treatment plan optimization aiming at reducing low-dose bath in the lungs could be an effective strategy for severe RIL mitigation.
Authors
- Serena Monti (ORCID: https://orcid.org/0000-0002-8777-7837)
- Radhe Mohan (ORCID: https://orcid.org/0000-0003-3746-4557)
- Laura Cella (ORCID: https://orcid.org/0000-0003-0058-4029)
- Ting Xu (ORCID: https://orcid.org/0000-0002-7851-3389)
- Zhongxing Liao (ORCID: https://orcid.org/0000-0002-2224-9478)
- Giuseppe Palma (ORCID: https://orcid.org/0000-0002-0210-268X)
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Institute of Biostructure and Bioimaging (IT)
- National Research Council (IT)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1016/j.phro.2025.100782
- Citations
- 1
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Cancer Institute