Single-cell transcriptomic landscape reveals complex cellular heterogeneity and dysregulated signaling pathways in nasopharyngeal carcinoma

This study employed single-cell transcriptomics to comprehensively elucidate the complexity of the NPC tumor microenvironment, providing new insights into the underlying mechanisms of disease pathogenesis and suggesting potential therapeutic targets. These findings lay the groundwork for the development of precision medicine approaches for NPC.

Authors

Institutions

Publication Details

Journal
Discover Oncology
Published
2025-05-19
DOI
https://doi.org/10.1007/s12672-025-02506-2
Citations
2
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
1.61
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Single-cell transcriptomic landscape reveals complex cellular heterogeneity and dysregulated signaling pathways in nasopharyngeal carcinoma

Zhenpeng Guan, Zhan Xu, Xiaoyan Zhang
2 citations
Discover Oncology
Single-cell and spatial transcriptomics
1.61
article

Single-cell transcriptomic landscape reveals complex cellular heterogeneity and dysregulated signaling pathways in nasopharyngeal carcinoma

Zhenpeng Guan, Zhan Xu, Xiaoyan Zhang
article en
2 citations

Abstract

This study employed single-cell transcriptomics to comprehensively elucidate the complexity of the NPC tumor microenvironment, providing new insights into the underlying mechanisms of disease pathogenesis and suggesting potential therapeutic targets. These findings lay the groundwork for the development of precision medicine approaches for NPC.

Discover OncologyVol. 16(1)
Zhejiang Yongning Pharma (China) (CN)
Life in Land
Openalex Percentile: Top 17%
Single-cell and spatial transcriptomics
1.61
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.