Study on the correlation between carbapenem-resistant Klebsiella pneumoniae infection strains and intestinal colonization strains in intensive care unit of a tertiary hospital in China
Nosocomial CRKP infection should focus on preventing intestinal colonization in hospitalized patients. Small single nucleotide polymorphisms differences indicated that the infected strain may have originated from the colonized strain, but some resistance genes or plasmids may have been obtained during this transformation process. bla<sub>KPC-2</sub>-carrying K. pneumoniae ST5422 was first reported in our study, and its genetic relationship was closely related to the clone strain ST11.
Authors
- Peipei Jin (ORCID: https://orcid.org/0000-0002-5787-1777)
- Zhenliang Wen (ORCID: https://orcid.org/0000-0002-7942-7060)
- Li Li (ORCID: https://orcid.org/0000-0001-6746-4297)
- Xiaohong Cai
- Changlin Yi
Institutions
- Ruijin Hospital (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1016/j.jgar.2025.05.004
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59
Funders
- Ruijin Hospital