Salvage therapy with an Albuvirtide-based antiretroviral regimen for multi-drug resistant HIV and drug-resistant HBV with renal impairment: a case report
This case underscores the potential value of individualized treatment strategies for patients with multidrug-resistant HIV and HBV co-infection complicated by renal impairment. The observed virological control following the use of novel agents such as Albuvirtide (ABT), in combination with second-generation integrase strand transfer inhibitors (INSTIs) like DTG, alongside renal-sparing antivirals, highlights the importance of designing optimized regimens based on resistance profiles and renal function. This personalized and adaptive therapeutic approach may offer clinical benefits in similarly complex scenarios.
Authors
- Linghua Li (ORCID: https://orcid.org/0000-0001-5711-8681)
- Yuan-Tao Liu (ORCID: https://orcid.org/0000-0002-5071-9780)
- Weiping Cai (ORCID: https://orcid.org/0000-0002-1287-0623)
- Yaozu He (ORCID: https://orcid.org/0000-0001-8919-534X)
- Yang Cao (ORCID: https://orcid.org/0000-0001-7787-8506)
- Baolin Liao
Institutions
- Singleron Biotechnologies (china) (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12985-025-02794-8
- Citations
- 1
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China