Enchondroma of the toe presenting as clubbing and painless longitudinal erythronychia

Enchondromas are frequently occurring cartilaginous tumors, accounting for 10-25% of all benign bone neoplasms. We present a distinctive case involving distal clubbing of the right third toenail with a painless, 5mm-wide red longitudinal streak. Clinical examination, nail matrix biopsy, and imaging confirmed the presence of an enchondroma in the distal phalanx. Although solitary enchondromas often present with pain or pathological fractures, asymptomatic cases like this one are quite rare. Given the low risk of malignant transformation, the patient chose regular magnetic resonance imaging (MRI) monitoring. This case highlights the need to consider enchondromas in the differential diagnosis of painless longitudinal erythronychia, an infrequent manifestation. Proper diagnosis is essential to differentiate these lesions from malignant chondrosarcomas, which have a different management approach.

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Publication Details

Journal
Dermatology Online Journal
Published
2025-05-19
DOI
https://doi.org/10.5070/d331265297
Primary Topic
Hypertrophic osteoarthropathy and related conditions
Type
article
Field-Weighted Citation Impact
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article

Enchondroma of the toe presenting as clubbing and painless longitudinal erythronychia

Brandon Levian, Daniel Mosallaei, Vignesh Ravi, Brittney DeClerck et al.
Dermatology Online Journal
Hypertrophic osteoarthropathy and related conditions
article

Enchondroma of the toe presenting as clubbing and painless longitudinal erythronychia

Brandon Levian, Daniel Mosallaei, Vignesh Ravi, Brittney DeClerck, Sebastian A. Cruz, Jenny Hu, Ming Terk Chiu
article en

Abstract

Enchondromas are frequently occurring cartilaginous tumors, accounting for 10-25% of all benign bone neoplasms. We present a distinctive case involving distal clubbing of the right third toenail with a painless, 5mm-wide red longitudinal streak. Clinical examination, nail matrix biopsy, and imaging confirmed the presence of an enchondroma in the distal phalanx. Although solitary enchondromas often present with pain or pathological fractures, asymptomatic cases like this one are quite rare. Given the low risk of malignant transformation, the patient chose regular magnetic resonance imaging (MRI) monitoring. This case highlights the need to consider enchondromas in the differential diagnosis of painless longitudinal erythronychia, an infrequent manifestation. Proper diagnosis is essential to differentiate these lesions from malignant chondrosarcomas, which have a different management approach.

Dermatology Online JournalVol. 31(2)
University of Southern California (US)
Openalex Percentile: Top 83%
Hypertrophic osteoarthropathy and related conditions
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