Cutaneous metastasis of serous ovarian carcinoma

Ovarian carcinoma ranks among the top causes of cancer-related fatalities among women in the United States [1]. In the spectrum of ovarian carcinomas, low-grade serous ovarian carcinoma (LGSOC) is a relatively rare form, constituting only 2-5% of all ovarian carcinomas [2]. Although metastasis to the peritoneum and other organs is frequently observed, cutaneous metastasis of ovarian carcinoma is uncommon, occurring in less than 4% of cases and occurring even less often in the serous subtype [3]. Owing to its rare and variable presentation, cutaneous involvement in ovarian carcinoma is particularly challenging to recognize. Patients presenting with skin lesions in the setting of a history of ovarian carcinoma should raise suspicion for cutaneous metastasis. We present a rare case of LGSOC with non-nodular cutaneous involvement presenting as asymptomatic erythematous papules and hyperpigmented patches on the upper chest, abdomen, and lower back.

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Publication Details

Journal
Dermatology Online Journal
Published
2025-05-19
DOI
https://doi.org/10.5070/d331265293
Primary Topic
Cancer Diagnosis and Treatment
Type
article
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article

Cutaneous metastasis of serous ovarian carcinoma

Kevin J. Gaddis, Jessica Padniewski, Andrew Truong, Ilhan Esse
Dermatology Online Journal
Cancer Diagnosis and Treatment
article

Cutaneous metastasis of serous ovarian carcinoma

Kevin J. Gaddis, Jessica Padniewski, Andrew Truong, Ilhan Esse
article en

Abstract

Ovarian carcinoma ranks among the top causes of cancer-related fatalities among women in the United States [1]. In the spectrum of ovarian carcinomas, low-grade serous ovarian carcinoma (LGSOC) is a relatively rare form, constituting only 2-5% of all ovarian carcinomas [2]. Although metastasis to the peritoneum and other organs is frequently observed, cutaneous metastasis of ovarian carcinoma is uncommon, occurring in less than 4% of cases and occurring even less often in the serous subtype [3]. Owing to its rare and variable presentation, cutaneous involvement in ovarian carcinoma is particularly challenging to recognize. Patients presenting with skin lesions in the setting of a history of ovarian carcinoma should raise suspicion for cutaneous metastasis. We present a rare case of LGSOC with non-nodular cutaneous involvement presenting as asymptomatic erythematous papules and hyperpigmented patches on the upper chest, abdomen, and lower back.

Dermatology Online JournalVol. 31(2)
University of Minnesota (US)
Zero hunger
Openalex Percentile: Top 83%
Cancer Diagnosis and Treatment
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Cutaneous metastasis of serous ovarian carcinoma — Kevin J. Gaddis, Jessica Padniewski, et al. · Dermatology Online Journal (2025) | TGRS Research Map | TGRS