SGLT2 Inhibitor with and without ALDosterone AntagonIst for Heart Failure with Preserved Ejection Fraction: Design Paper
SOGALDI-PEF will be the first trial in HFmr/pEF to test the combination of dapagliflozin/spironolactone vs dapagliflozin alone in a randomized manner. SOGALDI-PEF will provide information on the potential efficacy and safety of concomitant administration of spironolactone with dapagliflozin vs dapagliflozin alone in an elderly population with HFmr/pEF.
Authors
- Fernando Friões (ORCID: https://orcid.org/0000-0002-0856-8552)
- Cátia Costa (ORCID: https://orcid.org/0000-0001-7130-6283)
- Ana Oliveira (ORCID: https://orcid.org/0000-0002-4171-1971)
- Ricardo Fontes‐Carvalho (ORCID: https://orcid.org/0000-0003-2306-8393)
- Abhinav Sharma (ORCID: https://orcid.org/0000-0002-2346-8330)
- Marta Leite (ORCID: https://orcid.org/0000-0003-4067-3069)
- Francisca Saraiva (ORCID: https://orcid.org/0000-0001-7961-9962)
- Ana Filipa Ferreira (ORCID: https://orcid.org/0000-0003-2080-309X)
- João Tiago Guimarães (ORCID: https://orcid.org/0000-0003-4836-6311)
- Gualter Silva (ORCID: https://orcid.org/0000-0002-9508-6825)
- Joana Pimenta (ORCID: https://orcid.org/0000-0003-4930-0234)
- C Goncalves
- Francisco Vasques‐Nóvoa (ORCID: https://orcid.org/0000-0001-9701-8538)
- Diogo Santos‐Ferreira (ORCID: https://orcid.org/0000-0003-1428-1651)
- Pedro Marques (ORCID: https://orcid.org/0000-0003-0473-4864)
- Adelino Leite‐Moreira (ORCID: https://orcid.org/0000-0001-7808-3596)
- Catarina Pereira (ORCID: https://orcid.org/0000-0002-1131-8773)
- Joana Mascarenhas (ORCID: https://orcid.org/0000-0001-6745-6158)
- João Pedro Ferreira (ORCID: https://orcid.org/0000-0002-2304-6138)
- Pedro Henrique Fernandes Rodrigues (ORCID: https://orcid.org/0000-0002-5381-6615)
- Maria Inês Matos
- Ana Beatriz Batista
- Carla Sousa (ORCID: https://orcid.org/0000-0003-2477-7095)
- Arsénio Barbosa
- Faïez Zannad
- Jorge Almeida
- Inês Pereira‐Sousa
Institutions
- Instituto Superior de Contabilidade e Administracao do Porto (PT)
- Inserm (FR)
- Universidade do Porto (PT)
- McGill University Health Centre (CA)
- Hospital de São João (PT)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Centro Hospitalar de Vila Nova de Gaia (PT)
- French Clinical Research Infrastructure Network (FR)
- Polytechnic Institute of Porto (PT)
- Université de Lorraine (FR)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/ehf2.15294
- Citations
- 3
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 4.16
Funders
- AstraZeneca
- Fundação para a Ciência e a Tecnologia