Validation of Guidelines for Genetic Investigation of Myeloid Neoplasms with Germline Predisposition: Results from a Prospective Cohort Study
The implementation of the Nordic guidelines in a prospective Swedish cohort results in a high overall diagnostic yield (35%), proving the feasibility and utility of these or similar guidelines in a clinical setting.
Authors
- Jessika Nordin (ORCID: https://orcid.org/0000-0002-8414-2190)
- Johanna Ungerstedt (ORCID: https://orcid.org/0000-0002-0202-7296)
- Helena Ågerstam (ORCID: https://orcid.org/0009-0002-8216-3876)
- Elisabeth Ejerblad
- Martin Höglund (ORCID: https://orcid.org/0000-0003-2468-0226)
- Heléne Hallböök (ORCID: https://orcid.org/0000-0002-5764-3213)
- Bianca Tesi (ORCID: https://orcid.org/0000-0002-8253-2507)
- Martin Jädersten (ORCID: https://orcid.org/0000-0001-5217-3235)
- Linda Fogelstrand (ORCID: https://orcid.org/0000-0003-3698-8519)
- Eva Hellström‐Lindberg (ORCID: https://orcid.org/0000-0002-7839-3743)
- Ann‐Charlotte Thuresson (ORCID: https://orcid.org/0000-0002-4018-5551)
- Panagiotis Baliakas (ORCID: https://orcid.org/0000-0002-5634-7156)
- Thoas Fioretos (ORCID: https://orcid.org/0000-0002-3235-6154)
- Lucia Cavelier (ORCID: https://orcid.org/0009-0003-8195-370X)
- Jörg Cammenga
- Lovisa Vennström
- Ekaterina Kuchinskaya (ORCID: https://orcid.org/0009-0009-3347-6658)
- Stefan Deneberg (ORCID: https://orcid.org/0000-0003-1888-5567)
- Tatjana Pandzic (ORCID: https://orcid.org/0009-0006-9032-4616)
- Hege Garelius (ORCID: https://orcid.org/0000-0003-2553-7659)
- Sören Lehmann (ORCID: https://orcid.org/0000-0001-8374-8978)
- Claes Ladenvall (ORCID: https://orcid.org/0000-0002-7501-6598)
- Gisela Barbany (ORCID: https://orcid.org/0000-0003-3185-2962)
- Magnus Tobiasson (ORCID: https://orcid.org/0000-0002-3633-5852)
- Berivan Baskin
- Anna Norberg (ORCID: https://orcid.org/0000-0003-2947-8879)
- Vladimir Lazarević (ORCID: https://orcid.org/0000-0002-1782-4423)
- Fredrik Persson (ORCID: https://orcid.org/0000-0002-5374-4770)
- Anna Robelius (ORCID: https://orcid.org/0000-0002-8853-1863)
Institutions
- Linköping University (SE)
- Uppsala University (SE)
- Karolinska University Hospital (SE)
- Uppsala University Hospital (SE)
- Lund University (SE)
- Science for Life Laboratory (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- Department of Medical Sciences (RU)
- Skåne University Hospital (SE)
- Linköping University Hospital (SE)
- University of Gothenburg (SE)
- Umeå University (SE)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-4251
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Swedish Cancer Foundation
- Cancerfonden
- Kommunfullmäktige, Stockholms Stad
- Barncancerfonden
- Uppsala Universitet
- Svenska Läkaresällskapet
- Science for Life Laboratory
- Stockholm läns landsting
- Region Uppsala
- Center for Innovative Medicine