Evidence of greater immune aging among untreated HIV slow progressors than antiretroviral-controlled people living with HIV

Our findings indicate that despite natural host control of HIV replication, slow progressors show evidence of disproportionately advanced immune aging. This reinforces the potential benefit of ART and emphasizes the need to both diagnose slow progressors and study their potential age-related comorbidities.

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Publication Details

Journal
Journal of Infection
Published
2025-05-19
DOI
https://doi.org/10.1016/j.jinf.2025.106511
Citations
2
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
4.51

Funders

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article

Evidence of greater immune aging among untreated HIV slow progressors than antiretroviral-controlled people living with HIV

Anthony Y.Y. Hsieh, Hélène C. F. Côté, Renying Cai, Cécile Tremblay et al.
2 citations
Journal of Infection
HIV-related health complications and treatments
4.51
article

Evidence of greater immune aging among untreated HIV slow progressors than antiretroviral-controlled people living with HIV

Anthony Y.Y. Hsieh, Hélène C. F. Côté, Renying Cai, Cécile Tremblay, Nicole F. Bernard
article en
2 citations

Abstract

Our findings indicate that despite natural host control of HIV replication, slow progressors show evidence of disproportionately advanced immune aging. This reinforces the potential benefit of ART and emphasizes the need to both diagnose slow progressors and study their potential age-related comorbidities.

Journal of InfectionVol. 91(1)
University of British Columbia (CA), McGill University Health Centre (CA), Centre Hospitalier de l’Université de Montréal (CA)
Canadian HIV Trials Network, Canadian Institutes of Health Research, Canadian Institutes of Health Research, Fonds de Recherche du Québec - Santé
Good health and well-being
Openalex Percentile: Top 6%
HIV-related health complications and treatments
4.51
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