Impact of a microfluidic-based selection device on sperm deoxyribonucleic acid fragmentation and intracytoplasmic sperm injection cycles
This study provides valuable information on the use of MSSD for noninvasive sperm selection. When MSSD was used, we observed a reduction in sperm DNA fragmentation and an enhancement in the number of usable embryos in our own cycles. These findings could be compatible with a reduced capacity to repair sperm damage due to poorer oocyte quality caused by advanced age.
Authors
- María Luisa Pardiñas (ORCID: https://orcid.org/0000-0002-6381-2888)
- Rocío Rivera‐Egea (ORCID: https://orcid.org/0000-0002-8097-1629)
- María José de los Santos (ORCID: https://orcid.org/0000-0003-1394-8661)
- David Ortega-Jaén (ORCID: https://orcid.org/0009-0008-6837-9308)
- J.M. De los Santos (ORCID: https://orcid.org/0009-0007-2031-8779)
- Ángel Martín (ORCID: https://orcid.org/0000-0002-2824-2496)
- Julia Gil (ORCID: https://orcid.org/0009-0004-9830-3153)
- Thamara Viloria (ORCID: https://orcid.org/0009-0007-1072-9523)
- Juan Gilés (ORCID: https://orcid.org/0000-0001-9666-970X)
- Carmen Vidal
Institutions
- Valencian Infertility Institute (ES)
- Leitat Technological Center (ES)
- Instituto de Investigación Sanitaria La Fe (ES)
Publication Details
- Journal
- F&S Science
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1016/j.xfss.2025.05.002
- Citations
- 3
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 5.09
Funders
- Generalitat Valenciana
- INCLIVA Instituto de Investigación Sanitaria