Immunohistochemical Expression of p53 in Epithelial Ovarian Carcinoma and Its Correlation with Clinicopathological Parameters
Our study highlights the significant association of p53 mutations with a family history and histological subtypes of EOC. Elevated preoperative CA-125 levels are associated with advanced-stage and high-grade serous carcinomas. Moreover, higher-grade serous ovarian carcinomas are significantly associated with the presence of p53 mutations, providing valuable insights into pathogenesis and potential treatment strategies.
Authors
- Noor-e-Ferdous Noor-e-Ferdous
- Farzana Sharmin (ORCID: https://orcid.org/0000-0001-8085-0889)
- Towhidul Islam (ORCID: https://orcid.org/0000-0002-8402-0740)
- Jannatul Ferdous (ORCID: https://orcid.org/0000-0003-0738-3983)
- Khairun Nahar
- Latifa Akhter
Institutions
- Bangladesh Medical University (BD)
Publication Details
- Journal
- South Asian Journal of Cancer
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1055/s-0045-1809307
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00