Exploration of the association of antidiabetic drugs with urolithiasis: A drug-targeted Mendelian randomization study

This study provided evidence for a potential causal link between <i>KCNJ11</i>-mimicked sulfonylureas and the reduced risk of urolithiasis. Given the limitations of this study, it is essential to investigate further using the latest data from large-scale genetic studies and relevant clinical data to validate our findings from the MR study.

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Publication Details

Journal
Asian journal of urology
Published
2025-05-19
DOI
https://doi.org/10.1016/j.ajur.2025.03.012
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
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article

Exploration of the association of antidiabetic drugs with urolithiasis: A drug-targeted Mendelian randomization study

Yingying Yang, Qiancheng Mao, Ming Liu, Xidong Wang et al.
1 links
Asian journal of urology
Kidney Stones and Urolithiasis Treatments
article

Exploration of the association of antidiabetic drugs with urolithiasis: A drug-targeted Mendelian randomization study

Yingying Yang, Qiancheng Mao, Ming Liu, Xidong Wang, Tianqi Wang, Jitao Wu
article en

Abstract

This study provided evidence for a potential causal link between <i>KCNJ11</i>-mimicked sulfonylureas and the reduced risk of urolithiasis. Given the limitations of this study, it is essential to investigate further using the latest data from large-scale genetic studies and relevant clinical data to validate our findings from the MR study.

Asian journal of urologyVol. 13(1)
Qingdao University (CN), Yuhuangding Hospital (CN)
Good health and well-being
Openalex Percentile: Top 82%
Kidney Stones and Urolithiasis Treatments
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