Reduced SARS-CoV-2 vaccine-specific antibody response associated with high clozapine doses in schizophrenia spectrum disorders

High doses of clozapine (>350 mg/day) in patients with schizophrenia and schizoaffective disorders are associated with a diminished immune response to SARS-CoV-2 spike protein vaccination.

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Publication Details

Journal
Brain Behavior & Immunity - Health
Published
2025-05-19
DOI
https://doi.org/10.1016/j.bbih.2025.101016
Citations
1
Primary Topic
SARS-CoV-2 and COVID-19 Research
Type
article
Field-Weighted Citation Impact
1.40

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article

Reduced SARS-CoV-2 vaccine-specific antibody response associated with high clozapine doses in schizophrenia spectrum disorders

Diego Palao, Teresa Sagués, Itziar Montalvo, Patricia Pontón et al.
1 citations
Brain Behavior & Immunity - Health
SARS-CoV-2 and COVID-19 Research
1.40
article

Reduced SARS-CoV-2 vaccine-specific antibody response associated with high clozapine doses in schizophrenia spectrum disorders

Diego Palao, Teresa Sagués, Itziar Montalvo, Patricia Pontón, Antonio Berenguer, Javier Labad, Virginia Soria, Raquel Rodríguez‐González, Juan Francisco Delgado, Germà Julià, Albert Rodrigo-Parés, Indira Bhambi
article en
1 citations

Abstract

High doses of clozapine (>350 mg/day) in patients with schizophrenia and schizoaffective disorders are associated with a diminished immune response to SARS-CoV-2 spike protein vaccination.

Brain Behavior & Immunity - HealthVol. 46
Universitat Autònoma de Barcelona (ES), Instituto de Salud Carlos III (ES), Centro de Investigación Biomédica en Red de Salud Mental (ES), Maresme Health Consortium (ES), Hospital de Sabadell (ES), Institute of Research and Innovation Parc Tauli (ES)
Centres de Recerca de Catalunya, Generalitat de Catalunya
Good health and well-being
Openalex Percentile: Top 20%
SARS-CoV-2 and COVID-19 Research
1.40
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