Advancements in catalytic hydrogenation of nitrocyclohexane to cyclohexanone oxime

Cyclohexanone oxime serves as a crucial intermediate in the synthesis of caprolactam, which is an essential precursor for manufacturing nylon fibers, high-performance engineering plastics, and specialized plastic films. Catalytic hydrogenation of nitrocyclohexane to cyclohexanone oxime has been documented to be an atom-economical, green and environmentally friendly process. In this review, we first introduce the current design rules of catalysts for catalytic hydrogenation of nitrocyclohexane in terms of both active metals and supports. Secondly, we discuss the influence of solvent effects on the cyclohexanone oxime from the nitrocyclohexane conversion. In addition, we concisely discuss typically proposed reaction pathways for the hydrogenation of nitrocyclohexane to produce cyclohexanone oxime. Finally, we provide our perspectives on some issues for catalytic conversion of nitrocyclohexane to cyclohexanone oxime in the future. We provide our perspectives on some issues for catalytic hydrogenation of nitrocyclohexane to cyclohexanone oxime in the future. • We introduce the current design rules of catalysts for catalytic hydrogenation of nitrocyclohexane in terms of both active metals and supports. • We discuss the influence of solvent effects on the selectivity of cyclohexanone oxime from the nitrocyclohexane hydrogenation. • We concisely discuss typically proposed reaction pathways for the hydrogenation of nitrocyclohexane to produce cyclohexanone oxime.