Neuro-Behçet’s Syndrome: A Case Report

Behçet's syndrome is a systemic vasculitis characterized by recurrent oral and genital ulcers, uveitis, and often involvement of multiple organ systems. Neurological involvement is a rare complication of Behçet's syndrome and is associated with significant morbidity and mortality. Neuro-Behçet's syndrome (NBS) is a combination of neurologic manifestations in a patient with Behçet's syndrome, including movement disorders, myelopathic syndrome, intracranial hypertension, and a multiple sclerosis-like presentation. Diagnosis of NBS can be challenging due to the wide range of clinical presentations. Although previous research has aided in advancing the understanding of the pathophysiology and treatment of systemic Behçet's syndrome, there is a lack of randomized controlled studies involving the treatment of NBS. This case report describes a patient with NBS who experienced a complex hospital course, highlighting the need for a multidisciplinary team approach to address various complications.

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Publication Details

Journal
Cureus
Published
2025-05-19
DOI
https://doi.org/10.7759/cureus.84421
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
0.00
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article

Neuro-Behçet’s Syndrome: A Case Report

Kristen Kenny, D. Leroy, Cassie Konja, Elaine Ognjanovski et al.
Cureus
Ocular Diseases and Behçet’s Syndrome
article

Neuro-Behçet’s Syndrome: A Case Report

Kristen Kenny, D. Leroy, Cassie Konja, Elaine Ognjanovski, Silvia Menkes
article en

Abstract

Behçet's syndrome is a systemic vasculitis characterized by recurrent oral and genital ulcers, uveitis, and often involvement of multiple organ systems. Neurological involvement is a rare complication of Behçet's syndrome and is associated with significant morbidity and mortality. Neuro-Behçet's syndrome (NBS) is a combination of neurologic manifestations in a patient with Behçet's syndrome, including movement disorders, myelopathic syndrome, intracranial hypertension, and a multiple sclerosis-like presentation. Diagnosis of NBS can be challenging due to the wide range of clinical presentations. Although previous research has aided in advancing the understanding of the pathophysiology and treatment of systemic Behçet's syndrome, there is a lack of randomized controlled studies involving the treatment of NBS. This case report describes a patient with NBS who experienced a complex hospital course, highlighting the need for a multidisciplinary team approach to address various complications.

CureusVol. 17(5)
Henry Ford Health System (US)
Zero hunger
Openalex Percentile: Top 82%
Ocular Diseases and Behçet’s Syndrome
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Neuro-Behçet’s Syndrome: A Case Report — Kristen Kenny, D. Leroy, et al. · Cureus (2025) | TGRS Research Map | TGRS