Two cases of noncompaction of ventricular myocardium with ischemic stroke

Cardiogenic cerebral embolism is a well-known cause of ischemic stroke, typically associated with conditions like atrial fibrillation and acute myocardial infarction.However, left ventricular noncompaction (LVNC) is a rare but recognized cause of ischemic stroke, particularly in younger individuals.Case 1: A man in his 30s presented with sudden right hemiplegia and articulation disorder.An MRI confirmed a new cerebral infarction, and transthoracic echocardiography (TTE) revealed a thickened and compacted layer at the apex of the left ventricle.Cardiac MRI supported the diagnosis of LVNC, indicating it as the likely source of embolism.Case 2: Another man in his 30s with worsening dyspnea was diagnosed with acute congestive heart failure.TTE showed reduced left ventricular contraction and trabecular formations.However, after 13 days, he developed right-sided weakness, and MRI confirmed the occurrence of a new cerebral infarction.LVNC was suspected as the underlying cause of the embolism in this case.LVNC is characterized by echocardiographic findings such as trabecular formations and blood-filled lesions within the myocardium.However, distinguishing true LVNC from remodeling-related trabecular-formation can be challenging.Therefore, when echocardiographic images resemble LVNC, it is crucial to consider the possibility of LVNC as a potential cause of ischemic stroke.

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Publication Details

Journal
Neurosonology
Published
2025-01-01
DOI
https://doi.org/10.2301/neurosonology.38.11
Primary Topic
Cardiomyopathy and Myosin Studies
Type
article
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article

Two cases of noncompaction of ventricular myocardium with ischemic stroke

Yusuke Morii, Teisuke Anzai, Tomonori Miyabe, Ryuta Okabe et al.
Neurosonology
Cardiomyopathy and Myosin Studies
article

Two cases of noncompaction of ventricular myocardium with ischemic stroke

Yusuke Morii, Teisuke Anzai, Tomonori Miyabe, Ryuta Okabe, Toshiaki Isogai, Ken Kato, Yasuhiro Kawachi, Hiroyuki Tanaka, Shinichiro Sakurai, Yuya MISUHASHI
article en

Abstract

Cardiogenic cerebral embolism is a well-known cause of ischemic stroke, typically associated with conditions like atrial fibrillation and acute myocardial infarction.However, left ventricular noncompaction (LVNC) is a rare but recognized cause of ischemic stroke, particularly in younger individuals.Case 1: A man in his 30s presented with sudden right hemiplegia and articulation disorder.An MRI confirmed a new cerebral infarction, and transthoracic echocardiography (TTE) revealed a thickened and compacted layer at the apex of the left ventricle.Cardiac MRI supported the diagnosis of LVNC, indicating it as the likely source of embolism.Case 2: Another man in his 30s with worsening dyspnea was diagnosed with acute congestive heart failure.TTE showed reduced left ventricular contraction and trabecular formations.However, after 13 days, he developed right-sided weakness, and MRI confirmed the occurrence of a new cerebral infarction.LVNC was suspected as the underlying cause of the embolism in this case.LVNC is characterized by echocardiographic findings such as trabecular formations and blood-filled lesions within the myocardium.However, distinguishing true LVNC from remodeling-related trabecular-formation can be challenging.Therefore, when echocardiographic images resemble LVNC, it is crucial to consider the possibility of LVNC as a potential cause of ischemic stroke.

NeurosonologyVol. 38(1)
Minamiaoyama Eye Clinic (JP), Tokyo Metropolitan Tama Medical Center (JP)
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Openalex Percentile: Top 81%
Cardiomyopathy and Myosin Studies
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