Factor X deficiency presenting as an intracranial bleed in a young infant
Inherited Factor X deficiency is a rare bleeding disorder. It is inherited in autosomal recessive manner. The genotype and the phenotype are variable. The management is tailored as per individual patient. We hereby report an infant with severe Factor X deficiency who presented with recurrent intracranial bleeding needing prophylactic replacement of Factor X in the form of Fresh Frozen Plasma (FFP). She is currently 18 months of age and is having age-appropriate growth and development.
Authors
- Dhaarani Jayaraman (ORCID: https://orcid.org/0000-0003-3210-6945)
- Ramya Uppuluri (ORCID: https://orcid.org/0000-0001-5771-8214)
- Rishab Bhurat (ORCID: https://orcid.org/0009-0005-6961-0709)
- Julius Xavier Scott (ORCID: https://orcid.org/0000-0003-2390-7230)
- Sri Gayathri Shanmugam (ORCID: https://orcid.org/0000-0002-3204-6981)
- Sanyukta Sandeep Ghodke
- Rajakumar Padur Sivaraman (ORCID: https://orcid.org/0000-0002-9129-9786)
- Febe Renjitha Suman (ORCID: https://orcid.org/0000-0002-2539-7847)
Institutions
- Apollo Hospitals (IN)
- Sri Ramachandra Institute of Higher Education and Research (IN)
Publication Details
- Journal
- Pediatric Hematology Oncology Journal
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1016/j.phoj.2025.100454
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00