From genes to therapy: a lipid Metabolism-Related genetic risk model predicts HCC outcomes and enhances immunotherapy
The risk model constructed using lipid metabolism-related genes could effectively predict prognosis and was related to the immunosuppressive microenvironment and ICB immunotherapy. The hub genes related to the risk model were potential therapeutic targets.
Authors
- Tengfei Chao (ORCID: https://orcid.org/0000-0002-2920-3915)
- Ting Xiao (ORCID: https://orcid.org/0000-0002-7502-4395)
- Wei Yao (ORCID: https://orcid.org/0000-0002-4054-5916)
- Lei Xu (ORCID: https://orcid.org/0000-0002-3573-8334)
- Huihua Xiong
Institutions
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12885-025-14306-6
- Citations
- 2
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 2.64