Use of valproic acid by fathers before conception

A post-authorisation safety study found an elevated risk of neurological developmental disorders among children of men who were using valproic acid before the conception. In view of these results, the European Medicines Agency (EMA) has recommended precautionary measures. How strong is the evidence for this association, are there any other risks, what are the benefits of valproic acid, and are the precautionary measures that are recommended by the EMA appropriate?

Authors

Mélou Jansen (ORCID: https://orcid.org/0000-0002-3263-3123)

Publication Details

Journal: Geneesmiddelenbulletin
Published: 2025-01-01
DOI: https://doi.org/10.35351/gebu.2025.3.8
Primary Topic: Pharmacological Effects and Toxicity Studies
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

Use of valproic acid by fathers before conception

Mélou Jansen

Jan 1, 2025

Geneesmiddelenbulletin

Pharmacological Effects and Toxicity Studies

article

Use of valproic acid by fathers before conception

Mélou Jansen

January 1, 2025article en

Abstract

GeneesmiddelenbulletinVol. e2025.3.8(3)

Zero hunger

Openalex Percentile: Top 85%

Pharmacological Effects and Toxicity Studies

DOI Open Access PDF OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Use of valproic acid by fathers before conception — Mélou Jansen · Geneesmiddelenbulletin (2025) | TGRS Research Map | TGRS