Transcriptomic Profiles in Nasal Epithelium in Youth With Asthma

To the Editor A recent study1 provided insights into youth asthma heterogeneity using nasal epithelial transcriptomics. However, we have concerns about the endotype classification and T helper 2 (T2)–related molecular pathways examined in this study.

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Publication Details

Journal
JAMA
Published
2025-05-19
DOI
https://doi.org/10.1001/jama.2025.3311
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Transcriptomic Profiles in Nasal Epithelium in Youth With Asthma

Chung‐Chih Liao, Ching‐Mao Chang, Chung‐Pei Ma
JAMA
Asthma and respiratory diseases
article

Transcriptomic Profiles in Nasal Epithelium in Youth With Asthma

Chung‐Chih Liao, Ching‐Mao Chang, Chung‐Pei Ma
article en

Abstract

To the Editor A recent study1 provided insights into youth asthma heterogeneity using nasal epithelial transcriptomics. However, we have concerns about the endotype classification and T helper 2 (T2)–related molecular pathways examined in this study.

JAMAVol. 333(24)
Chang Gung University (TW), Taipei Veterans General Hospital (TW), Chung Shan Medical University Hospital (TW)
Zero hunger
Openalex Percentile: Top 86%
Asthma and respiratory diseases
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