Trigeminal Trophic Syndrome: A Visual Diagnosis

A 53-year-old male, a chronic alcoholic without other comorbidities, presented with progressive, recalcitrant ulceration of the left ala nasi, with extension to the cheek and forehead on the same side, over a period of two-months. Four months earlier, he had been involved in a road traffic accident and sustained a left cerebellar infarct and left lateral medullary syndrome. This resulted in slurred speech, involuntary upper limb tremors, and a tendency to sway to the left side while walking, but without any injury to the left side of his face. The patient reported a history of pruritus and persistent dysesthesia, which led to frequent rubbing and scratching, culminating in ulceration on the left side of his face. On cutaneous examination, a sharply demarcated superficial ulcer measuring 5 × 3 cm was observed on the left zygomatic region and left ala nasi, following the distribution of the V2 branch of the trigeminal nerve. Additionally, a similar ulcer measuring 6 × 2 cm was also noted on the frontal region, corresponding to the distribution of the V1 branch of the trigeminal nerve [Figure 1]. Neurological examination confirmed trigeminal paraesthesia and a diminished corneal reflex. Ophthalmic examination of the left eye revealed grade 4 cicatricial entropion of the lower eyelid, a corneal ulcer measuring 9 × 4.7 mm with stromal infiltrates, and corneal edema.Figure 1: Ulceration of the left ala nasi with extension to the adjacent cheek and forehead on the same sideThe patient was diagnosed with trigeminal trophic syndrome, based on clinical features, including facial paraesthesia, a prolonged history of repetitive physical manipulation of the affected area, and the history of head injury. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.

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Journal
Indian Dermatology Online Journal
Published
2025-05-19
DOI
https://doi.org/10.4103/idoj.idoj_890_24
Primary Topic
Trigeminal Neuralgia and Treatments
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article
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article

Trigeminal Trophic Syndrome: A Visual Diagnosis

Akshay Meena, Malathi Munisamy, Tirekha Suryamprakasam Vimala
Indian Dermatology Online Journal
Trigeminal Neuralgia and Treatments
article

Trigeminal Trophic Syndrome: A Visual Diagnosis

Akshay Meena, Malathi Munisamy, Tirekha Suryamprakasam Vimala
article en

Abstract

A 53-year-old male, a chronic alcoholic without other comorbidities, presented with progressive, recalcitrant ulceration of the left ala nasi, with extension to the cheek and forehead on the same side, over a period of two-months. Four months earlier, he had been involved in a road traffic accident and sustained a left cerebellar infarct and left lateral medullary syndrome. This resulted in slurred speech, involuntary upper limb tremors, and a tendency to sway to the left side while walking, but without any injury to the left side of his face. The patient reported a history of pruritus and persistent dysesthesia, which led to frequent rubbing and scratching, culminating in ulceration on the left side of his face. On cutaneous examination, a sharply demarcated superficial ulcer measuring 5 × 3 cm was observed on the left zygomatic region and left ala nasi, following the distribution of the V2 branch of the trigeminal nerve. Additionally, a similar ulcer measuring 6 × 2 cm was also noted on the frontal region, corresponding to the distribution of the V1 branch of the trigeminal nerve [Figure 1]. Neurological examination confirmed trigeminal paraesthesia and a diminished corneal reflex. Ophthalmic examination of the left eye revealed grade 4 cicatricial entropion of the lower eyelid, a corneal ulcer measuring 9 × 4.7 mm with stromal infiltrates, and corneal edema.Figure 1: Ulceration of the left ala nasi with extension to the adjacent cheek and forehead on the same sideThe patient was diagnosed with trigeminal trophic syndrome, based on clinical features, including facial paraesthesia, a prolonged history of repetitive physical manipulation of the affected area, and the history of head injury. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.

Indian Dermatology Online JournalVol. 16(4)
Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Openalex Percentile: Top 84%
Trigeminal Neuralgia and Treatments
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