Nuclear fragile X mental retardation-interacting protein 1-mediated ribophagy regulates immune function of dendritic cells in polymicrobial sepsis
These findings suggest that NUFIP1 regulates ER stress through the EIF2AK3-ATF4-damage-inducible transcript 3 pathway, highlighting its critical regulatory role in sepsis. Thus, NUFIP1 represents a new target for sepsis therapy.
Authors
- Shuting Wei (ORCID: https://orcid.org/0000-0001-5127-1247)
- Pengyue Zhao (ORCID: https://orcid.org/0000-0002-7813-1604)
- Yu Duan (ORCID: https://orcid.org/0009-0006-3133-403X)
- Ren-qi Yao
- Liyu Zheng
- Ning Dong (ORCID: https://orcid.org/0000-0003-0188-5165)
- Yong-ming Yao (ORCID: https://orcid.org/0000-0002-3564-4012)
- Lei Zheng (ORCID: https://orcid.org/0000-0002-8342-5236)
- Yao Wu (ORCID: https://orcid.org/0000-0003-4172-6994)
- Mengyao Wu (ORCID: https://orcid.org/0009-0005-1662-2239)
- Peng-yi He
Institutions
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Burns & Trauma
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/burnst/tkaf034
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China
- General Hospital of People’s Liberation Army