Ocular Manifestations in Reactions in Leprosy Patients

Purpose: To evaluate the spectrum and prevalence of ocular manifestations in patients with reactional states of Hansen's disease (leprosy) and to assess associated visual outcomes.Methods: A cross -sectional observational study was conducted on 45 patients with reactional leprosy at LLRM Medical College, Meerut.Ocular examinations included visual acuity, slit -lamp biomicroscopy, corneal sensation testing, ocular surface staining, and fundus evaluation.Results: Ocular manifestations were present in 66.7% of patients.The most affected structures included the cornea (80%), lens (50%), and adnexa (madarosis 56.6%).Patients who discontinued treatment showed the highest rates of blindness (11%) and severe visual impairment (18%).Complete adherence to multidrug therapy (MDT) correlated with preserved vision in all cases.Conclusion: Ocular involvement in leprosy is frequent and significantly impacts visual morbidity, particularly during reactional episodes.Early identification, interdisciplinary care, and sustained therapy are pivotal to preserving visual outcomes.