Dynamic deployment of H2A.Z positive nucleosome mediated transcriptomic plasticity within vascular smooth muscle cell
Vascular SMCs dynamically deployed H2A.Z-positive nucleosomes extending continuously downstream transcription start sites on different genes to support their transcriptional adjustability, which served as an important mechanism mediating cellular plasticity.
Authors
- Chao Yu (ORCID: https://orcid.org/0000-0002-9129-2218)
- Wei Shen (ORCID: https://orcid.org/0000-0002-2420-8311)
- Yan Wang (ORCID: https://orcid.org/0000-0003-0671-7312)
- Jia Song (ORCID: https://orcid.org/0000-0001-6039-6340)
- Jiaxin Huang (ORCID: https://orcid.org/0000-0001-7232-9313)
Institutions
- Tianjin University of Science and Technology (CN)
- Xiamen University (CN)
- First Affiliated Hospital of Xiamen University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Dian Diagnostics (China) (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12864-025-11679-7
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province
- Fujian Provincial Department of Science and Technology
- Xiamen University
- Southwest Medical University