Association between MYCN gene polymorphisms and neuroblastoma susceptibility: a case-control study in Chinese children from Jiangsu Province
Our study indicated that MYCN gene polymorphisms are significantly associated with neuroblastoma susceptibility in the eastern Chinese population and that high expression of the MYCN gene may suggest a poor prognosis. Nevertheless, further verification should be conducted with large-scale and well-designed studies to confirm our findings.
Authors
- Jiaming Chang (ORCID: https://orcid.org/0000-0003-2326-0449)
- Jing He (ORCID: https://orcid.org/0000-0002-1954-2892)
- Xinxin Zhang (ORCID: https://orcid.org/0000-0002-9048-2263)
- Jiabin Liu (ORCID: https://orcid.org/0000-0002-6090-2415)
- Mengzhen Zhang (ORCID: https://orcid.org/0000-0002-0019-7320)
- Yu Ouyang
- Chunlei Zhou (ORCID: https://orcid.org/0000-0002-0137-3314)
- Wenli Zhang
Institutions
- Liuzhou Maternal and Child Health Hospital (CN)
- Guangzhou Women and Children Medical Center (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s12885-025-14310-w
- Citations
- 1
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project
- Basic and Applied Basic Research Foundation of Guangdong Province