Trio Whole Exome Sequencing in Chinese Childhood‐Onset Lupus Reveals Novel Candidate Genes
This study highlights the abundance of lupus-relevant rare gene variants in cSLE, supports frequent contribution of de novo variants to disease, and identifies genes that may constitute novel therapeutic targets of relevance to Chinese patients.
Authors
- Chengmei Xie (ORCID: https://orcid.org/0000-0001-7309-590X)
- Todor Arsov (ORCID: https://orcid.org/0000-0003-4149-752X)
- Nan Shen (ORCID: https://orcid.org/0000-0002-5875-4417)
- Jingjing Tan (ORCID: https://orcid.org/0000-0001-6086-6517)
- Carola G. Vinuesa (ORCID: https://orcid.org/0000-0001-9799-0298)
- Yuke He (ORCID: https://orcid.org/0000-0002-6716-198X)
- Yuting Qin (ORCID: https://orcid.org/0000-0001-7506-2060)
- Philip Wu (ORCID: https://orcid.org/0000-0002-8861-6226)
- Huihua Ding (ORCID: https://orcid.org/0000-0002-7530-8953)
- Xiaoqian Wu (ORCID: https://orcid.org/0000-0003-1566-3811)
- Guojun Hou (ORCID: https://orcid.org/0000-0003-3974-4667)
- Qian Shen (ORCID: https://orcid.org/0000-0003-1899-6937)
- Thuvaraka Ware (ORCID: https://orcid.org/0000-0002-8713-3329)
- T. Daniel Andrews (ORCID: https://orcid.org/0000-0003-3922-6376)
- Pingjing Zhang (ORCID: https://orcid.org/0000-0002-6129-4685)
- Soon‐Min Hong
- Lanfang Cao
- Jianyang Ma (ORCID: https://orcid.org/0000-0002-4203-700X)
Institutions
- Australian National University (AU)
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- The Francis Crick Institute (GB)
- Goce Delcev University (MK)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/art.43243
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67