Development of a Protocol for Long‐Term Ex Vivo Normothermic Machine Perfusion of Rodent Livers
This is the first study to report LT-NMP of rodent livers up to 5 days. Using our protocol, rat livers could reliably be supported until 72 h. This model provides a greater opportunity to investigate novel therapeutics to assess, optimize, and regenerate liver grafts for transplantation.
Authors
- Chuanmin Wang (ORCID: https://orcid.org/0000-0002-3532-4318)
- Anita Niu (ORCID: https://orcid.org/0000-0002-5807-3240)
- Carlo Pulitanò (ORCID: https://orcid.org/0000-0002-4420-4107)
- Michael Crawford (ORCID: https://orcid.org/0000-0002-9194-5346)
- Ngee‐Soon Lau (ORCID: https://orcid.org/0000-0002-2254-8574)
- Mark Ly
- Geoffrey W. McCaughan (ORCID: https://orcid.org/0000-0002-1483-1636)
- Mark D. Gorrell (ORCID: https://orcid.org/0000-0002-0528-2604)
- Paul Yousif
- Daniel Babekuhl
Institutions
- The University of Sydney (AU)
- Royal Prince Alfred Hospital (AU)
- Centenary Institute (AU)
Publication Details
- Journal
- Artificial Organs
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1111/aor.15024
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Sydney