Quinine Sulfate for Muscle Cramps in Amyotrophic Lateral Sclerosis: A Randomized, Double‐Blind Crossover Trial
Our findings suggest the potential efficacy of quinine sulfate in reducing muscle cramp intensity and frequency in ALS patients. However, the small sample size (n = 7) limits generalizability. Larger, multicenter studies are needed to confirm these results and fully assess its safety, serious adverse events, and therapeutic potential.
Authors
- Christoph Neuwirth (ORCID: https://orcid.org/0000-0002-1874-8872)
- Ursula A. Schneider
- Markus Weber (ORCID: https://orcid.org/0000-0002-5538-9274)
- C Vogt (ORCID: https://orcid.org/0009-0000-8347-0259)
Institutions
- Kantonsspital St. Gallen (CH)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/mus.28440
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00