Long‐Term Dynamic Changes of Alanine Aminotransferase Levels Are Associated With Liver‐Related Events in Nucleos(t)ide Analogue‐Treated Chronic Hepatitis B Patients in China
On-treatment ALT levels were significantly correlated with the prognosis of CHB. ALT ≤ 23 U/L for men and ≤ 16 U/L for women were identified as the optimal thresholds during NA treatment, suggesting that CHB patients should strive for a lower ALT level beyond the traditional normal range.
Authors
- Ning Yu (ORCID: https://orcid.org/0009-0009-1820-3205)
- Henry Lik‐Yuen Chan (ORCID: https://orcid.org/0000-0002-7790-1611)
- Yongpeng Chen (ORCID: https://orcid.org/0000-0002-9015-9861)
- Terry Cheuk‐Fung Yip (ORCID: https://orcid.org/0000-0002-1819-2464)
- Jian Sun (ORCID: https://orcid.org/0000-0001-5320-227X)
- Rong Fan (ORCID: https://orcid.org/0000-0002-5922-483X)
- Jinlin Hou (ORCID: https://orcid.org/0000-0001-8230-8583)
- Jimmy Che‐To Lai (ORCID: https://orcid.org/0000-0002-5749-1598)
- Xieer Liang (ORCID: https://orcid.org/0000-0002-0862-3291)
- Vicki Wing‐Ki Hui (ORCID: https://orcid.org/0000-0002-6538-4098)
- Zhihong Liu (ORCID: https://orcid.org/0000-0003-1142-3589)
- Grace Lai–Hung Wong (ORCID: https://orcid.org/0000-0002-2863-9389)
- Jie Peng (ORCID: https://orcid.org/0000-0003-0928-3134)
- Junhua Yin
- Vincent Wai‐Sun Wong (ORCID: https://orcid.org/0000-0003-2215-9410)
- Chun-Xiu Zhong
Institutions
- Chinese University of Hong Kong (HK)
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1111/apt.70195
- Citations
- 4
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- Basic and Applied Basic Research Foundation of Guangdong Province