MULti‐TImepoint VElocity‐selective Reconciled with Spatially‐sElective (MULTIVERSE) ASL: Improving robustness to both shortened and prolonged arterial transit time
This novel and straightforward approach improves the accuracy and precision of the fitted CBF and ATT over an extended range of ATT, which is not possible with existing ASL methods. Brain scans from healthy subjects demonstrated the feasibility and reliability of the technique, highlighting the clinical potential of ASL-based perfusion mapping in various altered physiological and pathological conditions.
Authors
- Anja Soldan (ORCID: https://orcid.org/0000-0002-6193-0418)
- Dapeng Liu (ORCID: https://orcid.org/0000-0002-4432-3202)
- Martin A. Lindquist (ORCID: https://orcid.org/0000-0003-2289-0828)
- Marilyn Albert (ORCID: https://orcid.org/0000-0002-8167-8985)
- Doris D M Lin (ORCID: https://orcid.org/0000-0002-6001-2383)
- Dan Zhu (ORCID: https://orcid.org/0000-0002-0940-1519)
- Feng Xu (ORCID: https://orcid.org/0000-0001-7958-3787)
- Qin Qin (ORCID: https://orcid.org/0000-0002-6432-2944)
Institutions
- Kennedy Krieger Institute (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1002/mrm.30540
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Division of Cancer Prevention, National Cancer Institute
- National Heart and Lung Institute
- National Institute on Aging
- National Institute of Neurological Disorders and Stroke
- National Institute of Biomedical Imaging and Bioengineering