Spatiotemporal single-cell analysis elucidates the cellular and molecular dynamics of human cornea aging
As the first comprehensive spatiotemporal atlas, our work provides a valuable resource for understanding tissue homeostasis in the human cornea and advances research on corneal pathology, transplantation, senescence and regenerative medicine in the context of corneal aging.
Authors
- Yajing Wen (ORCID: https://orcid.org/0000-0002-4432-2816)
- Ying Feng (ORCID: https://orcid.org/0000-0003-4993-1431)
- Meng Zhou (ORCID: https://orcid.org/0000-0001-5187-9084)
- Yu Xia
- Zicheng Zhang (ORCID: https://orcid.org/0000-0002-5203-3328)
- Peter S. Reinach (ORCID: https://orcid.org/0000-0002-3494-4523)
- Yuanyuan Du (ORCID: https://orcid.org/0000-0002-8293-328X)
- Yining Sun
- Dan Jiang (ORCID: https://orcid.org/0000-0002-3830-3379)
- Ke Li (ORCID: https://orcid.org/0000-0002-0243-1811)
- Wei Chen (ORCID: https://orcid.org/0000-0002-4040-6721)
- Ruoqi Wang (ORCID: https://orcid.org/0009-0009-3189-4549)
- Shuang Xie (ORCID: https://orcid.org/0000-0003-4759-4160)
- Qinxiang Zheng (ORCID: https://orcid.org/0000-0003-0011-3702)
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
Publication Details
- Journal
- Genome Medicine
- Published
- 2025-05-19
- DOI
- https://doi.org/10.1186/s13073-025-01475-z
- Citations
- 9
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 12.24